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Shigeo Nakamura Selected Research

Fullerenes

3/2022A pyridinium‑type fullerene derivative suppresses primary effusion lymphoma cell viability via the downregulation of the Wnt signaling pathway through the destabilization of β‑catenin.
1/2019Synthesis and antitumor activity of novel pyridinium fullerene derivatives.
10/2016Novel fullerene derivatives as dual inhibitors of Hepatitis C virus NS5B polymerase and NS3/4A protease.
8/2014Pyrrolidinium fullerene induces apoptosis by activation of procaspase-9 via suppression of Akt in primary effusion lymphoma.
1/2013Anti-influenza activity of c60 fullerene derivatives.
11/2012Fullerene derivative prevents cellular transformation induced by JAK2 V617F mutant through inhibiting c-Jun N-terminal kinase pathway.
6/2010Biological safety of water-soluble fullerenes evaluated using tests for genotoxicity, phototoxicity, and pro-oxidant activity.

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Shigeo Nakamura Research Topics

Disease

68Lymphoma (Lymphomas)
07/2022 - 09/2000
68Neoplasms (Cancer)
12/2021 - 09/2000
27Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
05/2022 - 01/2005
22B-Cell Lymphoma (Lymphoma, B Cell)
05/2022 - 07/2004
20T-Cell Lymphoma (Lymphoma, T Cell)
01/2021 - 06/2003
18Marginal Zone B-Cell Lymphoma (MALT Lymphoma)
08/2019 - 09/2000
13Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma)
06/2018 - 06/2003
12Lymphoproliferative Disorders (Lymphoproliferative Disorder)
12/2021 - 05/2002
12Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
02/2021 - 11/2002
12Hodgkin Disease (Hodgkin's Disease)
01/2021 - 07/2005
10Thrombocytopenia (Thrombopenia)
01/2020 - 01/2007
10Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral)
01/2019 - 08/2004
9Lymphadenopathy
07/2014 - 12/2003
8Infections
01/2021 - 10/2004
8Disease Progression
08/2020 - 07/2005
8Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
09/2018 - 02/2004
7Carcinoma (Carcinomatosis)
05/2020 - 01/2005
7Autoimmune Diseases (Autoimmune Disease)
06/2018 - 04/2002
7Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated)
05/2014 - 02/2002
6Extranodal NK-T-Cell Lymphoma
05/2014 - 02/2004
6Leukemia
12/2013 - 06/2003
6Carcinogenesis
07/2013 - 12/2005
5Burkitt Lymphoma (Burkitt's Lymphoma)
10/2021 - 01/2002
5Ulcer
10/2021 - 06/2018
5Immunoglobulin G4-Related Disease
07/2020 - 02/2012
5Edema (Dropsy)
10/2019 - 01/2005
5Fever (Fevers)
10/2019 - 01/2005
5Anemia
03/2012 - 01/2004
4Inflammation (Inflammations)
01/2018 - 01/2014
4Non-Hodgkin Lymphoma (Lymphosarcoma)
01/2006 - 09/2000
4Hypergammaglobulinemia (Hyperimmunoglobulinemia)
01/2006 - 12/2003
3Fibrosis (Cirrhosis)
10/2019 - 01/2018
3Renal Insufficiency (Renal Failure)
10/2019 - 01/2018
3Familial primary gastric lymphoma
08/2019 - 09/2000
3Multi-centric Castleman's Disease
03/2019 - 06/2016
3Spontaneous Remission
01/2019 - 09/2005
3Stomach Neoplasms (Stomach Cancer)
11/2018 - 01/2004
3Insulin Resistance
01/2017 - 01/2014
3Adenocarcinoma
06/2016 - 04/2005
3Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2015 - 08/2004
3Epstein-Barr Virus Infections
01/2011 - 07/2003
3Necrosis
01/2009 - 01/2005
3Myelodysplastic Syndromes (Myelodysplastic Syndrome)
12/2008 - 02/2008
3Chromosome Aberrations (Chromosome Abnormalities)
06/2008 - 01/2005
3Mycosis Fungoides
10/2004 - 06/2003
2Rheumatoid Arthritis
04/2022 - 01/2019
2Primary Effusion Lymphoma
03/2022 - 08/2014

Drug/Important Bio-Agent (IBA)

22Rituximab (Mabthera)FDA Link
02/2021 - 06/2004
16Proteins (Proteins, Gene)FDA Link
12/2021 - 01/2005
16Methotrexate (Mexate)FDA LinkGeneric
12/2021 - 01/2003
13DNA (Deoxyribonucleic Acid)IBA
12/2021 - 05/2002
12Biological ProductsIBA
05/2022 - 12/2005
10RNA (Ribonucleic Acid)IBA
12/2021 - 04/2004
10Doxorubicin (Adriamycin)FDA LinkGeneric
01/2020 - 06/2004
9Pharmaceutical PreparationsIBA
01/2019 - 04/2004
9ParaffinIBA
07/2006 - 02/2002
8LigandsIBA
12/2021 - 12/2018
8Anaplastic Lymphoma KinaseIBA
06/2018 - 06/2003
7FullerenesIBA
03/2022 - 06/2010
7Immunoglobulins (Immunoglobulin)IBA
02/2014 - 04/2002
6Messenger RNA (mRNA)IBA
01/2018 - 06/2003
6Cyclin D1IBA
05/2013 - 07/2003
5Interleukin-6 (Interleukin 6)IBA
01/2022 - 02/2002
5T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2021 - 01/2013
5Immunoglobulin G (IgG)IBA
07/2020 - 02/2012
5AntigensIBA
01/2015 - 01/2002
5Asparaginase (Elspar)FDA Link
01/2015 - 05/2008
5AutoantibodiesIBA
01/2008 - 12/2003
5Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA
05/2006 - 01/2002
4B7-H1 AntigenIBA
01/2021 - 07/2018
4Cisplatin (Platino)FDA LinkGeneric
05/2020 - 06/2016
4Prednisolone (Predate)FDA LinkGeneric
01/2020 - 01/2005
4Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2020 - 06/2005
4Immunoglobulin A (IgA)IBA
01/2020 - 04/2002
4Vincristine (Oncovin)FDA LinkGeneric
01/2020 - 06/2005
4Etoposide (VP 16)FDA LinkGeneric
12/2017 - 05/2008
4SteroidsIBA
01/2013 - 03/2011
4IfosfamideFDA LinkGeneric
11/2012 - 05/2008
4Chemokine ReceptorsIBA
04/2011 - 08/2004
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2021 - 02/2002
3Reticulin (Reticular Fiber)IBA
10/2019 - 01/2018
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2019 - 06/2010
3L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
03/2017 - 01/2006
3Dexamethasone (Maxidex)FDA LinkGeneric
01/2017 - 05/2008
3Biomarkers (Surrogate Marker)IBA
11/2014 - 05/2005
3Granzymes (Granzyme)IBA
03/2013 - 10/2005
3Member 1 Subfamily B ATP Binding Cassette TransporterIBA
03/2013 - 05/2008
3Dacarbazine (DIC)FDA LinkGeneric
01/2013 - 12/2010
3Serotonin (5 Hydroxytryptamine)IBA
04/2008 - 09/2006
2Hematoxylin (Haematoxylon)IBA
07/2022 - 01/2007
2InterferonsIBA
01/2022 - 12/2021
2MucinsIBA
10/2021 - 05/2015

Therapy/Procedure

36Drug Therapy (Chemotherapy)
10/2020 - 11/2002
28Therapeutics
10/2021 - 08/2002
8Radiotherapy
06/2015 - 11/2002
5Stem Cell Transplantation
05/2022 - 08/2013
3Aftercare (After-Treatment)
01/2019 - 05/2009
3Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation)
01/2017 - 07/2005
3Transplantation
01/2012 - 07/2005
2Radioimmunotherapy
02/2021 - 01/2009